Steps Towards Functional Synthetic Biology

EasyChair Preprint 9044

Abstract

While synthetic biology has made great progress in methods for modular assembly of genetic sequences and in engineering biological systems with a wide variety of functions, current paradigms entangle sequence and functionality in a manner that makes abstraction difficult, reduces engineering flexibility, and impairs predictability and design reuse. Functional Synthetic Biology proposes a roadmap to overcome these limits by focusing on behavior descriptions, predictability, flexibility, and risk reduction, so synthetic biologists can more effectively share successes and avoid failures. The iGEM community, like other synthetic biology communities, faces challenges in the effective sharing and reuse of biological devices. These are particularly acute for iGEM, since iGEM teams need to execute projects in only a few months and many team members have little prior experience. At the same time, barriers for adoption are lowered by the culture of openness, sharing, and reuse that is encouraged by iGEM. For these reasons, the iGEM Engineering Committee has been working to implement the early phases of the Functional Synthetic Biology roadmap in the context of iGEM’s annual DNA distribution.

Keyphrases: Continuous Integration, functional synthetic biology, iGEM

@booklet{EasyChair:9044,
  author    = {Ibrahim Aldulijan and Jacob Beal and Sonja Billerbeck and Jeff Bouffard and Gaël Chambonnier and Nikolaos Delkis and Isaac Guerreiro and Martin Holub Martin Holub and Daisuke Kiga and Jacky Loo and Paul Ross and Vinoo Selvarajah and Noah Sprent and Gonzalo Vidal and Alejandro Vignoni},
  title     = {Steps Towards Functional Synthetic Biology},
  howpublished = {EasyChair Preprint 9044},
  year      = {EasyChair, 2022}}